Maltreatment associated with mental and physical health mediated by inflammation

Maltreatment include the following: maternal rejection, harsh disciple, disruptive caregivers changes, physical abuse and sexual abuse. Maltreatment has been associated with increased inflammation. Despite accounting for stress, maltreatment independently predicts inflammation. Depression also accounts for inflammation . Maltreated individuals are twice as likely to develop recurrent depression. They also show poorer response to treatments. Thus, maltreatment effects are evident on mental and physical health of individuals and can be mediated by the mechanisms of inflammation.

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